Randomized Controlled Trial Evidence of Cost-Effectiveness of a Multifaceted AKI Intervention Approach

Acute kidney injury (AKI) is linked to elevated healthcare usage and greater expenses. The Tackling AKI study, a pragmatic, multicenter, stepped-wedge cluster randomized trial, showcased a decrease in hospital length of stay following the introduction of a comprehensive AKI intervention (featuring e-alerts, care bundle, and an education program). Our aim was to assess whether these changes would translate into cost reductions.

In the article, our team utilized a decision-analytic tree model from the payer perspective (National Health Service in the United Kingdom). We performed cost-effectiveness analyses using a probabilistic sensitivity analysis, accounting only for direct medical costs, and leveraged clinical data from the Tackling AKI study, including inputs and economic and utility data derived from relevant published literature.

Read now “Randomized Controlled Trial Evidence of Cost-Effectiveness of a Multifaceted AKI Intervention Approach.”

Our experts behind the article:

• Giacomo Basadonna
• Chris Rao
• Luís Korrodi-Gregório

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